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Kingchem China: Your strategic partner for specialty chemical manufacturing and RSM production

Kingchem's state-of-the-art facilities in China are strategically designed to tackle the complex challenges of pharmaceutical development and production.

Our integrated approach combines cutting-edge technology, world-class expertise, and a commitment to quality, providing you with a strategic advantage in the global pharmaceutical landscape.

Fuxin, Liaoning, China: Large-scale specialty chemical manufacturing

Our expansive Fuxin facility is your gateway to large-scale production of regulatory starting materials (RSMs), intermediates, building blocks, and specialty chemicals. We specialize in complex chemistries, offering tailored solutions for diverse industries.

Key capabilities

  • Advanced technologies: Our facility is equipped for fluorination (HF, KF, SF4), chlorination, phosgenation, hydrogenation, cryogenic reactions, Grignard reactions, and more.
  • Large-scale production: Our extensive reactor capacity (up to 10,000L for fluorination) and over 50 distillation columns ensure efficient and reliable production of your specialty chemicals.
  • Integrated R&D: Our on-site R&D center, equipped with advanced analytical tools like NMR, LC-MS, and GC-MS, ensures seamless process development, optimization, and scale-up.
  • Dalian R&D: Our Dalian R&D center offers process development and custom synthesis. The expert team in Dalian has the resources to build a custom and cost-effective manufacturing route to your target molecule.

Locations

Strategically located in Fuxin, Liaoning Province, China, our facility provides seamless access to major transportation routes and a highly skilled workforce, ensuring efficient production and global delivery of your specialty chemicals and RSMs.

Dalian, Liaoning Province, China is home to our distinguished research and development center. Scientists in Dalian have the equipment and expertise to develop scalable processes to support all Fuxin operations. The strategic science city of Dalian has enabled a culture of innovation which we continue to support.

Quality assurance

Kingchem adheres to the highest quality standards. Our Fuxin facility maintains:

  • ISO certifications: ISO 9001:2015 (Quality Management) and ISO 14001:2015 (Environmental Management) certifications demonstrate our commitment to quality and sustainability.
  • Rigorous audits: We actively engage with leading pharmaceutical and chemical companies through regular audits, fostering a culture of continuous improvement and ensuring our processes meet the most stringent industry standards.
  • ICH Q7 compliance: We incorporate elements of ICH Q7 guidelines into our quality management system to meet the specific needs of our pharmaceutical clients.

Equipment and facilities at Dalian

Our Dalian Research & Development Center provides integrated and cost-effective process R&D services including design of practical synthesis, improvement of existing chemistry, and development of commercial processes.

Kingchem’s 40,000 ft2 (4,000 m2) research and development facility located in Dalian (China) operates 100 research hoods and 35 walk-in hoods. Dalian’s kilo lab facilities include 50-L and 20-L reactors, thin-film evaporator, fractional distillation equipment, and rotary evaporator. This allows us to rapidly scale up lab process to produce advanced intermediates in kilogram scale.

  • Analysis Suite: Our analytical group uses advanced instruments including NMR, ICP-OES, LC-MS, GC-MS, HPLC, GC, DSC and UV-Vis for product identification, impurity identification, in-process control, product testing, and release.
  • Process Optimization: We continue to introduce advanced instrumentation, such as RC1 for process optimization, EasyMax and RSD for process safety tests.
  • Expert Team: Kingchem’s 100-member team of process development chemists and engineers excel at synthesizing advanced intermediates and developing commercial processes to be run at Kingchem’s manufacturing facility in Fuxin. Typically, staff from Dalian will travel to the production facility to ensure the chemistry transfers smoothly.

Equipment and capabilities at Fuxin

Our expansive 37-acre (150,000 m2) facility is equipped with state-of-the-art technology and diverse capabilities to address your complex chemical challenges:

  • Advanced technologies: Our facility is a leader in fluorination (HF, KF, SF4), chlorination, phosgenation, hydrogenation, cryogenic lithiations, and heterocycle chemistry. We also offer a range of other supporting technologies, such as acylation, alkylation, bromination, chiral synthesis, and more.
  • Large-scale reactors (300L – 10,000L): Our versatile reactors, including those with glass lining, stainless steel, and Hastelloy construction, handle diverse chemical reactions at scale. We specialize in fluorination with reactors up to 10,000 liters.
  • Distillation expertise: With over 50 distillation columns, including those with up to 30 theoretical plates, we ensure precise separation and purification of your products.
  • Kilo labs: Our dedicated kilo labs facilitate seamless scale-up from development to commercial production.
  • Technology center: Our 2,200 m2 technology center houses cutting-edge analytical equipment, including NMR, LC-MS, and GC-MS, for comprehensive quality control and analysis.
  • Specialized Workshops: Our facility includes workshops dedicated to photochlorination, fluorination, hydrogenation, electrochemistry, and more.

Ready to partner with Kingchem?

At Kingchem, we are your strategic partner in specialty chemical manufacturing and RSM production. We combine our technical expertise, state-of-the-art facilities, and commitment to quality to provide you with a competitive advantage in the market. Contact us today to discuss how we can support your next project.

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