Click on a topic below to go to the FAQs about that topic.
- Analytical Services: What analytical services does Kingchem offer?
- Chemistries: What Chemistries does Kingchem offer?
- Confidentiality & IP Control: Can I share Intellectual Property (IP) with Kingchem?
- Core Technologies & Competencies: What does Kingchem's offer?
- C-TPAT: Is Kingchem C-TPAT certified?
- Custom Manufacturing Services: Does Kingchem offer custom manufacturing services?
- Dedicated Logistics and Delivery Services: What does Kingchem offer?
- Environmental Health & Safety: Is Kingchem concerned with Environmental Health & Safety (EHS)?
- Nutritionals: Why should I choose Kingchem for Nutritionals?
- Outsourcing Services: Does Kingchem use outsourcing services?
- Product Lines: Where can I find Kingchem's chemical product listings?
- Project Management: How will Kingchem handle my project?
- Quality Systems: What are Kingchem's Quality Systems?
- R&D Capabilities: What R&D capabilities does Kingchem offer?
- Where can I meet with Kingchem?
Analytical Services: What analytical services does Kingchem offer?
Kingchem’s analytical group is highly experienced and well equipped to support all R&D and production activities. Our group leader and staff have many years of experience in both fine chemical and CRO/CMO industries. A large number of Agilent HPLC/GC instruments serve as the primary tools for method development, validation, and in-process testing and control. Other available analytical instruments include GC-MS, LC-MS, NMR, FT-IR, UV-Vis for structure determination/identification, and DSC for thermal analysis.
We routinely perform method development and validation, release testing, and stability testing. In addition to supporting route-scouting and early research activities, we are also capable of performing production OOS investigations.
Kingchem analytical R&D is a part of the integrated service that supports process R&D and product launch.
Chemistries: What Chemistries does Kingchem offer?
Over the years, Kingchem has accumulated extensive experience with many challenging reactions for the preparation of lab samples to manufacturing in production scales.
- Chiral synthesis
- Dieckmann reaction
- Freidel-Crafts reaction
- Grignard reaction
- Halogenation (additional)
- Hoffman rearrangement
- Hydrazine chemistry
- Michael Addition
- Organolithium chemistry
- Suzuki coupling
- Ullmann reaction
Confidentiality & IP Control: Can I share Intellectual Property (IP) with Kingchem?
The importance of Intellectual Property protection can not be overstated. Kingchem takes extra precautions to protect our customers IP by:
- Having staff sign CDAs as a part of employment.
- Team training regarding handling confidential information and providing a secure environment.
- Assigning a specific project number in place of a customer’s name on documentation.
- Limiting the dissemination of information to management staff and assigning project leaders on a “need to know” basis.
- Separating duties during R&D, Process Development and Manufacturing as may be needed.
- Document security.
- Site security alarms, as well as separate security staff.
Core Technologies & Competencies: What does Kingchem's offer?
To review our core technologies & competencies, please visit our Core Technologies & Competencies page by clicking here.
C-TPAT: Is Kingchem C-TPAT certified?
Yes. Kingchem is fully C-TPAT certified and validated by the U.S. Customs and Border Protection agency. We maintain active compliance with the program to protect the supply chains of our business partners. For more information, please see our C-TPAT page by clicking here.
Custom Manufacturing Services: Does Kingchem offer custom manufacturing services?
In addition to core technologies like fluorinations, hydrogenations, photochlorinations, phosgenations and organometallic reactions, as a manufacturer Kingchem offers a wide range of chemical capabilities to enable the large scale production of complex organic compounds. Once the CDA is in place, any customer IP will be protected and the work will be carried out safely and efficiently. The technical staff at Kingchem’s Dalian R&D center specializes in chemical development of processes to be transitioned from the lab to pilot and production scale at Kingchem’s manufacturing site in Liaoning.
The R&D team can also design and optimize the processes to improve the economics, efficiency and safety profile. The manufacturing equipment at Liaoning includes pilot equipment (50-2000 l) and production equipment (500-5000 l) operating in both glass and stainless-steel lined vessels over a broad range of temperatures (-80 deg C to 300 deg C).
Kingchem’s Liaoning manufacturing plant operates to high industrial standards, maintaining ISO9001 and ISO14001 certification. On-going training programs ensure the workforce is safe and in compliance. Once the desired chemicals are prepared, the logistics team ensures that shipments follow international guidelines (MEP, REACH, TSCA, etc.) safely and efficiently.
To serve as an effective strategic partner for its customers, Kingchem has in place:
- An infrastructure for ready access to cost effective raw materials in China.
- R&D teams to provide necessary chemical design and support.
- Production facilities to produce advanced intermediates/specialty chemicals at multi-ton scale.
- Logistics teams to ensure the transfer of specialty chemicals to the customer.
Dedicated Logistics and Delivery Services: What does Kingchem offer?
Kingchem delivers product worldwide and has experienced staff in dedicated logistics operations in China which operates at all times with the full support of Kingchem’s US-based commercial and administrative headquarters in New Jersey, Kingchem’s Liaoning manufacturing plant and Kingchem’s R&D center in Dalian. As a team, we provide timely efficient delivery of goods with full documentation for receipt of delivery including, for example:
- Certificate of Analysis
- Tracings (GC or HPLC etc.)
- BSE-TSE statement
- Dangerous Goods Certificate
- Conformance to International transport regulations of air and sea freights
- TSCA, REACH or other regulatory statements provided
- C-TPAT Certification
Environmental Health & Safety: Is Kingchem concerned with Environmental Health & Safety (EHS)?
A special Environmental Health and Safety (EHS) department is in place to ensure conformity management, risk evaluation, work approvals and CAPA. Standard operational procedures (SOPs) and pre-arranged emergency plans are in place. All staff maintains a high level of EHS responsibility consciousness, knowledge and skills. In fact, Kingchem’s strong commitment to safe and effective Environmental Health and Safety (EHS) practices begins at the very top of our management structure which, in turn, provides the daily support necessary to promote the knowledge, skills and planning needed to ensure consistent EHS practices.
Kingchem’s Liaoning manufacturing plant (in the city of Fuxin, Liaoning Province, China) has proactive communications and cooperation with the local government emergency office, safety supervision bureau, firefighting department, and the environmental protection and public health bureaus. Twice, large-scale emergency drills have been successfully implemented together with these government offices in 2010 and 2011 to address firefighting and the possibility of leakage of HF/Cl2.
Kingchem believes in maintaining a proactive, conscientious responsibility for our staff, our company, our clients and our surrounding environment and society. Thus, Kingchem works to maintain and enhance its EHS goals of:
- Continually implementing further safety and green product processes.
- Continually upgrading EHS facilities.
- Continually improving EHS SOPs and employee training.
Nutritionals: Why should I choose Kingchem for Nutritionals?
The motto of Kingchem’s Nutritional division is “Balance and Harmony between Science and Nature.” At Kingchem, we are also firmly committed to the guiding principles of Quality, Customer Service, Dedication and Innovation. Our commitment continues through conscientiously chosen strategic partnerships with a select group of manufacturers from all around the world. Our partners provide a complementary array of products and services that set Kingchem apart from its competition. We routinely confirm the quality of our partner’s products by analyses at independent laboratories in the United States. Our pursuit of total quality is reflected in our product knowledge, technical expertise and responsible dealings with US government agencies.
Why else Kingchem for Nutritionals?
- Many products are in stock and available for immediate shipment.
- Independent laboratory results.
- Product liability insurance.
- Competitive prices.
- Technical assistance.
- Our greatest strength is understanding customer needs and responding immediately to their requests.
Outsourcing Services: Does Kingchem use outsourcing services?
Click here for information about Kingchem cGMP plant, currently in the design phase. For the technologies falling outside the current capabilities of Kingchem manufacturing such as fermentations, steroid production and cGMP work, Kingchem maintains a comprehensive and reliable network of skilled manufacturing alliances. All of Kingchem’s partners abide by strict international guidelines with respect to intellectual property and maintain high standards in operation of their manufacturing facilities.
Product Lines: Where can I find Kingchem's chemical product listings?
Please click here to go to our SEARCH OUR PRODUCTS page. Or, you can also use the Search Our Products button found at the top of every page.
Project Management: How will Kingchem handle my project?
Kingchem manages your project in an efficient and confidential manner by having procedures in place that protect your intellectual property and assess your initial inquiry through the evaluation and final manufacturing stages. Regular updates are provided as well as complete analytical analysis with Certificates of Analysis, Tracings and other required regulatory documentation.
Kingchem recognizes the importance of timely project updates, and Kingchem staff works to meet our customer’s needs regarding how to best manage project update reports. These updates will cover what has been done from the last review period as well as an agreed to path forward until project completion.
Your project is supported by Kingchem’s 50 well-trained, experienced chemists and engineers who hold a full range of academic and industrial credentials. Kingchem’s R&D center located in Dalian, China excels at synthesizing advanced intermediates and developing commercial processes to be run at Kingchem’s in-house manufacturing facility in Liaoning. The Liaoning plant also has a staff of 480 personnel standing ready to manufacture products meeting your specifications in the requested time line while working in conjunction with our Dalian R&D staff.
Quality Systems: What are Kingchem's Quality Systems?
A quality management system was established in 2002 for all operations including R&D, production, trade and supply chain. The conformity with GB/T19001 (idt ISO9001) of the quality management system has been in place since 2003.
In order to conform to the increasing requirements from some API clients, parts of ICH-Q7 were integrated with the quality management system in 2010. A special QA department is now in place. The number of customer complaints is getting smaller, there was only one complaint received in 2010 and in 2011. Kingchem has passed quality audits from top Chemical and pharmaceutical companies in recent years. We have been operating very close to ICH-Q7 standards, such as material management, cross contamination control, equipment qualification and maintaining, batch record, QC management, deviation management and change control management. In the last two years, we have successfully run several campaigns and delivered starting materials governed by quality agreements.
In the next few years, our major developmental goals are to enhance existing services and expand technical capabilities, to more closely meet client requirements worldwide.
R&D Capabilities: What R&D capabilities does Kingchem offer?
Kingchem’s Dalian Research & Development Center has the infrastructure in place to provide a full complement of R&D activities necessary to respond to the needs of the customer. Our experienced staff of 50 research chemists and engineers can perform process R&D to improve existing processes and design new processes in order to prepare complex organic compounds of interest in gram to multiple kilogram quantities. We have state of the art R&D facilities (from milliliter up to 50 L) and full access to scientific literature which allows us to design syntheses or to improve existing chemistries. As well, our research chemists and engineers excel at solving problems related to the synthesis of advanced intermediates and the subsequent scale up to commercial processes to be run at Kingchem’s manufacturing facility in Liaoning or at a customer’s facility.
The Dalian R&D facility is equipped with the necessary analytical instrumentation to support the synthesis and to confirm the identity and quality of the products. The chemists and engineers at the Dalian site interact closely with the staff at our Liaoning manufacturing facility for a smooth transition of processes to pilot and/or production scales. The staff is also responsible for developing the process to be scaled up at the Liaoning manufacturing facility. Typically, staff from Dalian will travel to Liaoning to ensure that processes transfer smoothly at the production facility.
Where can I meet with Kingchem?
To see our Trade Show page for upcoming shows around the world which we will attend, click here. (Please also see the Contact Us link at the top of the page.).